- Grayscale says Ethereum, Solana, BNB Chain, and Canton Network could gain most from the CLARITY Act.
- The firm links regulatory clarity to rising institutional adoption in tokenization, stablecoins, and DeFi markets.
- Canton Network stood out for institutional settlement activity, including DTCC pilots and tokenized asset infrastructure.
Grayscale identified Ethereum, Solana, BNB, and Canton Network as the blockchains best positioned for regulatory clarity under the CLARITY Act. The research note, published around May 21 and 22, followed the Senate Banking Committee’s 15-9 bipartisan vote on May 14 advancing the Digital Asset Market Clarity Act. According to Grayscale, the legislation could accelerate institutional adoption through tokenization, stablecoins, and decentralized finance infrastructure.
Ethereum, Solana And BNB Chain Lead Metrics
Grayscale said Ethereum remains the leading blockchain for tokenized assets with full on-chain functionality. The asset manager also ranked Solana and BNB Chain highly for stablecoin activity and DeFi engagement.
According to the report, the three networks lead in stablecoin supply, decentralized exchange activity, and total value locked. Grayscale linked those metrics to growing institutional demand for on-chain financial systems.
Meanwhile, the report tied those networks to broader tokenization trends already developing across crypto markets. Grayscale previously forecast stronger institutional participation in its December 2025 report titled “2026 Digital Asset Outlook: Dawn of the Institutional Era.”
The firm said the CLARITY Act could establish clearer registration rules and digital asset classifications. That framework, according to Grayscale, may provide clearer operating standards for crypto intermediaries and blockchain networks.
Canton Network Draws Institutional Focus
Canton Network appeared as the fourth blockchain in Grayscale’s list, replacing earlier reports that incorrectly named Cardano. Grayscale’s original research specifically identified Canton Network for institutional settlement and privacy-focused financial applications.
Notably, Canton Network hosts the DTCC’s tokenized Treasury pilot. The network also counts JPMorgan Chase, HSBC, and Visa among its validators.
According to recent Canton Network figures, the blockchain settles about $350 billion daily. The network also reported more than $6 trillion in tokenized real-world assets.
Avalanche, Base And Tron Also Make List
Grayscale also highlighted secondary beneficiaries connected to on-chain finance activity. Those networks included Avalanche, Base, Arbitrum, Hyperliquid, and Tron.
The report stated those blockchains maintain established DeFi ecosystems and active stablecoin usage. However, Grayscale placed them below Ethereum, Solana, BNB Chain, and Canton Network in tokenized asset exposure.
The CLARITY Act now moves toward a Senate floor vote. The bill still requires House reconciliation and presidential approval before becoming law.