
Drug discovery is a search problem. There are more possible molecules than anyone can test, so pharma picks a target, searches a narrow slice of chemical space with one team and one method, and hopes. @metanova_labs built Bittensor Subnet 68 to search it a different way. Anyone can submit candidates against a specified target, submissions get scored and ranked, the best ones win, and NOVA pulls the strongest into its own pipeline. Small molecules, nanobodies and algorithms are live now. No lab and no pharma job required to enter. What it's searching for is Agency Therapeutics, a proposed framework for drugs that improve the biological capacity to regulate yourself. Like how GLP-1s reduce what you have to resist, ADHD meds increase the capacity to act, and psychedelics may help better patterns stick. @EliLillyandCo booked $36.5 billion on Mounjaro and Zepbound last year selling drugs that make hunger easier to resist. They were built for metabolism, and that effect was a byproduct. NOVA is designed to find Agency Therapeutics on purpose, and the first hits from that search are already at a lab being tested. Imagine what it means when NOVA productizes its first drug out of an open competition.
