Fault-tolerant quantum computing just got a concrete deadline: 2028. The U.S. Department of Energy has launched Quantum Genesis, an initiative to develop the world's first scientifically relevant fault-tolerant quantum computer. The ambitious scope targets the low hundreds of logical qubits to solve real problems in chemistry, materials science, plasma physics, and high-energy physics. Three pillars define the effort: a DOE Q Competition to accelerate system development, a National Quantum Supercomputing User Facility offering multi-modality access, and focused R&D to identify breakthrough scientific applications. The facility will integrate directly with existing exascale HPC and AI infrastructure. What makes this notable is the specificity. This isn't a roadmap or a whitepaper — it's a competition with a timeline, a user facility with a mandate, and application-driven benchmarks. Setting concrete milestones for fault tolerance forces the entire ecosystem to align around deliverables rather than projections. The initiative signals that quantum computing's value proposition is being measured in scientific utility, not just qubit counts. Defining keystone scientific applications as the standard for evaluating systems is exactly the kind of framing that moves the field from promise to proof #QuantumComputing